Adapted from Comi, Clin Ther, 2009; Compston, Lancet, 2008; Fisniku, Brain, 2008; and Trapp, Neuroscientist, 1999.2,9-11
For illustrative purposes only.
Proportion of patients on first-line therapies with an inadequate response can vary based on criteria used. Some studies prior to 2010 show that up to two-thirds of patients may exhibit an inadequate response after relapsing MS treatment initiation.4,18,22
Leading physicians discuss the need to monitor disease activity to help guide treatment decisions.
CSF=cerebrospinal fluid; IgG=immunoglobulin G; IgM=immunoglobulin M; DMT=disease-modifying therapy; ARR=annualized relapse rate; EDSS=Expanded Disability Status Scale.